Chemical Biology, Bioinorganic and Medicinal Chemistry

The research activities in our laboratory involve organic/inorganic synthesis, enzyme mimetic studies and multidisciplinary approaches in the area of biomedical research. Our recent efforts are directed toward understanding the antioxidant activity of synthetic compounds in mammalian cells, the thyroid hormone metabolism and thyroid related disorders, development of molecular probes for the detection and quantification of reactive oxygen species in the cells and oxidative stress biomarkers. We have successfully established a chemistry laboratory for the organic/inorganic synthesis, characterization and in vitro activity based on UV-VIS, Fluorescence and LC-MS assays and a chemical (molecular) biology laboratory for protein expression, purification and cell-based studies. We created a unique multidisciplinary group for an efficient collaboration within the laboratory and outside to undertake challenging contemporary problems at the chemistry-biology interface.

Representative Publications