Sensitivity Enhancement in NMR by Nuclear Spin Hyperpolarization

Our research primarily focused on developing techniques to overcome two major drawbacks in NMR and MRI – (i) poor sensitivity and (ii) insufficient lifetime of nuclear spins. The research enables us in understanding nuclear spin dynamics in meticulous detail and consequently finding novel contrast agents and drugs for in vivo applications. We work in the forefront areas of nuclear spin hyperpolarization, a technique to dramatically improve nuclear spin sensitivity and consequently leading to huge signal enhancement in NMR and MRI. Experiments that otherwise may take hours to complete, can now be done in seconds. These development aids toward realizing miniaturized, cost-efficient, and portable NMR/ MRI machines for the future.

Representative Publications